Minimisation of aminoglycoside toxicity in patients with cystic fibrosis.

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چکیده

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Minimisation of aminoglycoside toxicity in patients with cystic fibrosis.

BACKGROUND There is evidence that administration of higher doses of aminoglycosides given less frequently improves the bactericidal effect and reduces the potential to cause side effects. To investigate this, a prospectively randomised open label therapeutic trial was undertaken in stratified groups of patients with cystic fibrosis to examine the efficacy and toxic potential of an aminoglycosid...

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ژورنال

عنوان ژورنال: Thorax

سال: 1996

ISSN: 0040-6376

DOI: 10.1136/thx.51.4.369